At the Intersection of DNA Replication and Genome Maintenance: from Mechanisms to Therapy
Subscribe in ParasocialFree on the App Store for iPhone, iPad and Mac. No subscription needed. Once it is installed, tap this link again and the show is yours. Already have it? Open in Parasocial.
About
The conference will represent a unique forum to discuss the most recent and unpublished findings on the basic biology of replication fork perturbation and repair as well as on our current understanding of how replicative stress drives cancer and aging. Session topics will include: Basic mechanisms at the replication fork, Replication-repair interface, Replication fork remodeling, Structural and single molecule analysis of replication/repair, Replication-transcription interface, Replication-recombination interface Chromatin, replication and genome maintenance, Difficult-to-replicate loci and telomers, Replication stress in cancer onset and therapy.
Also on
Recent episodes
- O. Fernandez-Capetillo - Mechanisms of resistance to anticancer therapies
- S. Mirkin - Mechanisms of genome instability mediated by interstitial telomeric sequences
- I. Whitehouse - Coupling of gene enhancers and replication origins
- A. Constantinou - A FANCM protein interaction screen reveals a pyrimidine catabolism enzyme required to prevent cell-intrinsic DNA replication stress
- J. Berger - Structural mechanisms for initiating DNA replication
- W. Yang - Molecular gymnastics during DNA translesion synthesis
- P. Pasero - SAMHD1 processes stalled forks and links DNA replication stress to inflammation
- D. Cortez - ETAA1 regulates ATR to maintain genome stability during DNA replication
- T. Carr - Mechanisms of replication-associated genome rearrangement
- P. Knipscheer - How does the Fanconi pathway promote unhooking of DNA interstrand crosslinks?